ZC3H8 抗体
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- 抗原 See all ZC3H8 抗体
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZC3H8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to ZC3H8 (zinc finger CCCH-type containing 8)
ZC3H8 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431 , HepG2 , Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.84 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
- 别名
- zinc finger CCCH-type containing 8 (ZC3H8 产品)
- 别名
- Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody
- 背景
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Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Cellular Localization: Nucleus - 分子量
- 34 kDa
- 基因ID
- 84524
- UniProt
- Q8N5P1
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