BCL2L1 抗体
(1 reference)Quick Overview for BCL2L1 抗体 (ABIN2856151)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 犬, 人, 小鼠, 大鼠
-
产品特性
-
Rabbit Polyclonal antibody to Bcl-X (BCL2-like 1)
Bcl-X antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Bcl-X. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibodyBCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibodyBCL2L1 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-209) antibodyBCL2L1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (N-Term) antibodyBCL2L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (pSer62) antibodyBCL2L1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: NIH-3T3 , PC-12
Validation: Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.45 mg/mL
-
缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
: "Caspase-3 cleaved p65 fragment dampens NF-κB-mediated anti-apoptotic transcription by interfering with the p65/RPS3 interaction." in: FEBS letters, Vol. 589, Issue 23, pp. 3581-7, (2016) (PubMed).
-
: "Caspase-3 cleaved p65 fragment dampens NF-κB-mediated anti-apoptotic transcription by interfering with the p65/RPS3 interaction." in: FEBS letters, Vol. 589, Issue 23, pp. 3581-7, (2016) (PubMed).
-
- BCL2L1 (BCL2-Like 1 (BCL2L1))
-
别名
- BCL2 like 1
-
背景
-
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Cellular Localization: Mitochondrion membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein, Cytoplasmic side , Mitochondrion membrane , Nucleus membrane -
分子量
- 26 kDa
-
基因ID
- 598
-
UniProt
- Q07817
-
途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
-
