NDUFS1 抗体 (Center)
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- 抗原 See all NDUFS1 抗体
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
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抗原表位
- Center
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NDUFS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- Chimpanzee
- 交叉反应 (详细)
- Chimpanzee (100 %)
- 产品特性
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Rabbit Polyclonal antibody to NDUFS1 (NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75 kDa (NADH-coenzyme Q reductase))
NDUFS1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human NDUFS1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product NDUFS1 Primary Antibody
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
- 说明
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Positive Control: HepG2 , mouse brain , rat brain
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy." in: Cell metabolism, Vol. 28, Issue 1, pp. 130-144.e7, (2019) (PubMed).
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Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy." in: Cell metabolism, Vol. 28, Issue 1, pp. 130-144.e7, (2019) (PubMed).
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- 抗原
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
- 别名
- NDUFS1 (NDUFS1 产品)
- 别名
- 5830412M15Rik antibody, 9930026A05Rik antibody, CI-75Kd antibody, CI-75k antibody, PRO1304 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antibody, NADH:ubiquinone oxidoreductase core subunit S1 antibody, Ndufs1 antibody, NDUFS1 antibody
- 背景
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The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency.
Cellular Localization: Mitochondrion inner membrane - 分子量
- 79 kDa
- 基因ID
- 4719
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