DDR2 抗体 (C-Term)
Quick Overview for DDR2 抗体 (C-Term) (ABIN2855450)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to DDR2 (discoidin domain receptor tyrosine kinase 2)
DDR2 antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DDR2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibody
DDR2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B11E4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 245-350) antibodyDDR2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 447-540) antibodyDDR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 578-817) antibodyDDR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17713 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 31-80) antibodyDDR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 816-843) antibodyDDR2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 277-377) antibodyDDR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation: KO/KD, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.43 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- discoidin domain receptor tyrosine kinase 2
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背景
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Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Cellular Localization: Membrane -
分子量
- 97 kDa
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基因ID
- 4921
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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