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MCL-1 抗体 (Center)

Name: MCL-1 抗体 (Center)
Brand: antibodies-online
SKU: ABIN2855261
Availability: OutOfStock

This anti-MCL-1 antibody is a 兔多克隆 antibody detecting MCL-1 in WB, IF, IHC (p) 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using MCL1, antibody at 1:250 dilution. (MCL-1 抗体 (Center))

IHC

WB Image Sample (30μg whole cell lysate) A:Raji , 10% SDS PAGE antibody diluted at 1:1000 (MCL-1 抗体 (Center))

IHC-P Image MCL1 antibody detects MCL1 protein at cytoplasm in mouse testis by immunohistochemical analysis. (MCL-1 抗体 (Center))

IHC

ICC/IF Image MCL1 antibody detects MCL1 protein at cytoplasm and nucleus by immunofluorescent analysis. (MCL-1 抗体 (Center))

MPT0B098 induces the cell cycle arrest and apoptosis. (MCL-1 抗体 (Center))

5 images

(2 references)

产品编号 ABIN2855261

发货至: 中国

Quick Overview for MCL-1 抗体 (Center) (ABIN2855261)

抗原

See all MCL-1 (MCL1) 抗体

MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MCL-1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Discover our top product MCL1 Primary Antibody

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Center

产品特性

Rabbit Polyclonal antibody to MCL1 (myeloid cell leukemia sequence 1 (BCL2-related))
MCL1 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human MCL1. The exact sequence is proprietary.

亚型

IgG
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Internal Region) antibody
MCL1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Internal Region) antibody
MCL1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 2-307) antibody
MCL1 适用: 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 1-350) antibody
MCL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody
MCL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IP 宿主: 兔 Monoclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 19-244) antibody
MCL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 120-220) antibody
MCL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody
MCL1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 8C6D4B1 unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 191-226) antibody
MCL1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 6-328) antibody
MCL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

说明

Positive Control: Raji

限制

仅限研究用
状态

Liquid

浓度

0.89 mg/mL

缓冲液

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Takino, Sato, Nagamine, Hori: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).

Peng, Cheng, Hsu, Wu, Kuo, Liou, Chang, Jin, Shiah: "MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158440, (2017) (PubMed).
抗原

MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

别名

MCL1

背景

The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

Cellular Localization: Membrane, Single-pass membrane protein (Potential) , Cytoplasm , Mitochondrion , Nucleus , nucleoplasm

分子量

37 kDa

基因ID

4170

途径

MAPK Pathway