LTBP4 抗体 (N-Term)
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- 抗原 See all LTBP4 抗体
- LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LTBP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to LTBP4 (latent transforming growth factor beta binding protein 4)
LTBP4 antibody [N1N2], N-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse brain , Positive Control: Mouse brain
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.07 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
- 别名
- latent transforming growth factor beta binding protein 4 (LTBP4 产品)
- 别名
- ARCL1C antibody, LTBP-4 antibody, LTBP4L antibody, LTBP4S antibody, 2310046A13Rik antibody, latent transforming growth factor beta binding protein 4 antibody, LTBP4 antibody, ltbp4 antibody, Ltbp4 antibody
- 背景
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Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]
Cellular Localization: Secreted , extracellular space , extracellular matrix - 分子量
- 173 kDa
- 基因ID
- 8425
- UniProt
- Q8N2S1
- 途径
- Hormone Transport, Growth Factor Binding
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