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HSP90AB1 抗体 (Internal Region)

HSP90AB1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855037
发货至: 中国
  • 抗原 See all HSP90AB1 抗体
    HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
    抗原表位
    • 16
    • 13
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    • 5
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    Internal Region
    适用
    • 130
    • 90
    • 79
    • 15
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    人, 小鼠, 大鼠
    宿主
    • 101
    • 28
    • 1
    克隆类型
    • 99
    • 31
    多克隆
    标记
    • 73
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    This HSP90AB1 antibody is un-conjugated
    应用范围
    • 103
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    猕猴, 牛
    交叉反应 (详细)
    Rhesus Monkey (100 %), Bovine (100 %)
    产品特性
    Rabbit Polyclonal antibody to HSP90 beta (heat shock protein 90 kDa alpha (cytosolic), class B member 1)
    HSP90 beta antibody [N2C2], Internal
    纯化方法
    Affinity purified by Protein A.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HSP90 beta. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product HSP90AB1 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: HeLaS3

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    5.43 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Galmozzi, Kok, Kim, Montenegro-Burke, Lee, Spreafico, Mosure, Albert, Cintron-Colon, Godio, Webb, Conti, Solt, Kojetin, Parker, Peluso, Pru, Siuzdak, Cravatt, Saez: "PGRMC2 is an intracellular haem chaperone critical for adipocyte function." in: Nature, Vol. 576, Issue 7785, pp. 138-142, (2020) (PubMed).

  • 抗原
    HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
    别名
    HSP90 beta (HSP90AB1 产品)
    别名
    D6S182 antibody, HSP84 antibody, HSP90B antibody, HSPC2 antibody, HSPCB antibody, GRP94 antibody, TRA1 antibody, hsp90b antibody, 90kDa antibody, AL022974 antibody, C81438 antibody, Hsp84 antibody, Hsp84-1 antibody, Hsp90 antibody, Hspcb antibody, Hsp70 antibody, Hsp70-1 antibody, Hsp70.1 antibody, hsp68 antibody, HSP90-BETA antibody, hsp90beta antibody, wu:fa29f01 antibody, wu:fa91e11 antibody, wu:fd59e11 antibody, wu:gcd22h07 antibody, HSP90 antibody, heat shock protein 90 alpha family class B member 1 antibody, heat shock protein 90 beta family member 1 antibody, Heat Shock Protein 90, endoplasmic reticulum antibody, heat shock protein 90B antibody, heat shock protein 90 alpha (cytosolic), class B member 1 antibody, heat shock protein 1B antibody, heat shock protein 90kDa alpha family class B member 1 S homeolog antibody, heat shock protein 90, alpha (cytosolic), class B member 1 antibody, HSP90AB1 antibody, HSP90B1 antibody, HSP90B antibody, hsp90ab1 antibody, Hsp90ab1 antibody, Hspa1b antibody, hsp90ab1.S antibody
    背景
    HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]

    Cellular Localization: Cytoplasm , Melanosome
    分子量
    83 kDa
    基因ID
    3326
    途径
    Regulation of Cell Size
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