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ADAM17 抗体 (C-Term)

The 兔 多克隆 anti-ADAM17 antibody is suitable to detect ADAM17 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN2855021
发货至: 中国
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Quick Overview for ADAM17 抗体 (C-Term) (ABIN2855021)

抗原

See all ADAM17 抗体
ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADAM17 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to ADAM17 (ADAM metallopeptidase domain 17)
    ADAM17 antibody [C2C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human ADAM17. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: K562 , Raw264.7 , Rat2 , HeLa

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.21 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

    别名

    ADAM metallopeptidase domain 17

    背景

    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

    Cellular Localization: Membrane

    分子量

    93 kDa

    基因ID

    6868

    UniProt

    P78536

    途径

    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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