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HLAG 抗体

HLAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854954
发货至: 中国
  • 抗原 See all HLAG 抗体
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    适用
    • 130
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    宿主
    • 92
    • 43
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    克隆类型
    • 95
    • 45
    多克隆
    标记
    • 93
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    This HLAG antibody is un-conjugated
    应用范围
    • 92
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to HLA-G (major histocompatibility complex, class I, G)
    HLA-G antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HLA-G. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product HLAG Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Molt-4

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.83 mg/mL
    缓冲液
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    别名
    major histocompatibility complex, class I, G (HLAG 产品)
    背景
    HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    38 kDa
    基因ID
    3135
    UniProt
    P17693
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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