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Lamin A/C 抗体

Name: Lamin A/C 抗体
Brand: antibodies-online
SKU: ABIN2854943
Availability: OutOfStock

This anti-Lamin A/C antibody is a 兔多克隆 antibody detecting Lamin A/C in WB, IF, IP, ICC 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 4+ publications.

WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 7. (Lamin A/C 抗体)

IHC-P Image Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, using Lamin A + C, antibody at 1:500 dilution. (Lamin A/C 抗体)

IHC

IHC-P Image Immunohistochemical analysis of paraffin-embedded RT2 xenograft, using Lamin A + C, antibody at 1:500 dilution. (Lamin A/C 抗体)

IHC

WB Image Lamin A + C antibody detects Lamin A + C protein by western blot analysis. (Lamin A/C 抗体)

IP Image Lamin A + C antibody immunoprecipitates Lamin A + C protein in IP experiments. (Lamin A/C 抗体)

IHC-P Image Immunohistochemical analysis of paraffin-embedded Mahlarvu xenograft, using Lamin A + C, antibody at 1:500 dilution. (Lamin A/C 抗体)

IHC

ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using Lamin A + C, antibody (Green) at 1:500 dilution. (Lamin A/C 抗体)

Nuclear factor (NF)-κB is involved in epidermal growth factor (EGF)-induced heme oxygenase (HO)-1 expression in HT-29 cells. (Lamin A/C 抗体)

8 images

(4 references)

产品编号 ABIN2854943

发货至: 中国

Quick Overview for Lamin A/C 抗体 (ABIN2854943)

抗原

See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Lamin A/C antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated

Discover our top product LMNA Primary Antibody

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to Lamin A + C
Lamin A + C antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human Lamin A + C. The exact sequence is proprietary.

亚型

IgG
anti-Lamin A/C (LMNA) (AA 403-572) antibody
LMNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (pSer392) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
KO Validated LMNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人 IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 4H7 unconjugated Recombinant Antibody

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Lamin A/C (LMNA) (AA 481-646) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 455-469) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 133A2 unconjugated

anti-Lamin A/C (LMNA) (C-Term) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 兔, 马, Hamster, 小鸡, 绵羊, 豚鼠, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 1-664) antibody
LMNA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: NIH-3T3
Validation: Comparison, KO/KD, Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.73 mg/mL

缓冲液

1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Zhang, Li, Guan, Zhou, Wang, Yang, Zhen, Dai, Zhao, Jiang, Xu: "MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation." in: Frontiers in physiology, Vol. 11, pp. 510, (2020) (PubMed).

Kuo, Ling, Chiang, Chung, Lee, Chu, Wu, Chen, Lai, Tsai, Cheng, Lin: "Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit." in: Theranostics, Vol. 9, Issue 9, pp. 2526-2540, (2020) (PubMed).

Bueno, Martínez-Morga, Martínez: "Non-proliferative neurogenesis in human periodontal ligament stem cells." in: Scientific reports, Vol. 9, Issue 1, pp. 18038, (2019) (PubMed).

Wu, Yen, Kou, Wu: "Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130599, (2016) (PubMed).
抗原

Lamin A/C (LMNA)

别名

lamin A/C

背景

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Cellular Localization: Nucleus

分子量

74 kDa

基因ID

4000

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus