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PTPN11 抗体 (C-Term)

Name: PTPN11 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN2854914
Availability: OutOfStock

This anti-PTPN11 antibody is a 兔多克隆 antibody detecting PTPN11 in WB 和 IHC (p). Suitable for 人.

WB Image SHP2 antibody detects PTPN11 protein by Western blot analysis. (PTPN11 抗体 (C-Term))

WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7. (PTPN11 抗体 (C-Term))

IHC-P Image SHP2 antibody detects PTPN11 protein at cytosol on BT483 xenograft by immunohistochemical analysis. (PTPN11 抗体 (C-Term))

IHC

IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft , using SHP2, antibody at 1:500 dilution. (PTPN11 抗体 (C-Term))

IHC

WB Image Sample (30 ug of whole cell lysate) A: Hela 7. (PTPN11 抗体 (C-Term))

5 images

产品编号 ABIN2854914

发货至: 中国

Quick Overview for PTPN11 抗体 (C-Term) (ABIN2854914)

抗原

See all PTPN11 抗体

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PTPN11 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated

Discover our top product PTPN11 Primary Antibody

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C-Term

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to SHP2 (protein tyrosine phosphatase, non-receptor type 11)
SHP2 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human SHP2. The exact sequence is proprietary.

亚型

IgG
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 514-593) antibody
PTPN11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 263-329) antibody
PTPN11 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D9 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
Verified PTPN11 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibody
PTPN11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21493 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-460) antibody
PTPN11 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr542) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
PTPN11 适用: 人, 犬 WB, FACS 宿主: 小鼠 Monoclonal 3F2 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
PTPN11 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated

应用备注

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: rat brain , Mouse brain
Validation: KO/KD

限制

仅限研究用
状态

Liquid

浓度

0.63 mg/mL

缓冲液

1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

别名

protein tyrosine phosphatase non-receptor type 11

背景

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Cellular Localization: Cytoplasm

分子量

68 kDa

基因ID

5781

UniProt

Q06124

途径

JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect