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Bestrophin 1 抗体

BEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854513
发货至: 中国
  • 抗原 See all Bestrophin 1 (BEST1) 抗体
    Bestrophin 1 (BEST1)
    适用
    • 26
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 21
    • 5
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bestrophin 1 antibody is un-conjugated
    应用范围
    • 17
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to Bestrophin 1 (bestrophin 1)
    Bestrophin 1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Bestrophin 1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BEST1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: NT2D1 , PC-3 , SK-N-SH

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Bestrophin 1 (BEST1)
    别名
    bestrophin 1 (BEST1 产品)
    别名
    CG6264 antibody, Dbest antibody, Dmel\\CG6264 antibody, anon-WO0118547.380 antibody, best antibody, dBest1 antibody, dbest1 antibody, dmBest1 antibody, BEST1 antibody, VMD2 antibody, best-1 antibody, ARB antibody, BEST antibody, BMD antibody, RP50 antibody, TU15B antibody, Bmd antibody, Vmd2 antibody, mBest1 antibody, Bestrophin 1 antibody, bestrophin 1 antibody, Best1 antibody, BEST1 antibody, best1 antibody, Bm1_25500 antibody
    背景
    This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

    Cellular Localization: Cell membrane
    分子量
    68 kDa
    基因ID
    7439
    UniProt
    O76090
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