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Tissue factor 抗体

KO Validated F3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854298
发货至: 中国
  • 抗原 See all Tissue factor (F3) 抗体
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    适用
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    宿主
    • 87
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    克隆类型
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    多克隆
    标记
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    This Tissue factor antibody is un-conjugated
    应用范围
    • 93
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to Coagulation factor III
    Coagulation factor III antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Coagulation factor III/Tissue Factor. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product F3 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validatio: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    别名
    coagulation factor III, tissue factor (F3 产品)
    别名
    CD142 antibody, TF antibody, TFA antibody, PRO1557 antibody, PRO2086 antibody, TFQTL1 antibody, f3 antibody, AA409063 antibody, Cf-3 antibody, Cf3 antibody, tf antibody, zgc:112151 antibody, coagulation factor III, tissue factor antibody, transferrin antibody, coagulation factor IIIa antibody, coagulation factor III antibody, tissue factor antibody, coagulation factor IIIb antibody, coagulation factor III (thromboplastin, tissue factor) S homeolog antibody, F3 antibody, TF antibody, f3a antibody, tf antibody, f3b antibody, f3.S antibody
    背景
    This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    33 kDa
    基因ID
    2152
    UniProt
    P13726
    途径
    Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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