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Bcl-2 抗体

BCL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854283
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 抗体
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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    多克隆
    标记
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    This Bcl-2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to BCL2 (apoptosis regulator Bcl-2)
    Bcl-2 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Bcl-2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BCL2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: BCL2-transfected 293T

    Validation: Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    BCL2 apoptosis regulator (BCL2 产品)
    背景
    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

    Cellular Localization: Mitochondrion outer membrane , Nucleus membrane , Endoplasmic reticulum membrane
    分子量
    26 kDa
    基因ID
    596
    UniProt
    P10415
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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