SEMA4D/CD100 抗体 (FITC)
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- 抗原 See all SEMA4D/CD100 (SEMA4D) 抗体
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This SEMA4D/CD100 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- Protein G agarose
- 免疫原
- Mouse CD100-Fc fusion protein
- 克隆位点
- MMA-12
- 亚型
- IgG1
- Top Product
- Discover our top product SEMA4D Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS, 1 % BSA, 0.09 % NaN3
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8 °C.
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- 抗原
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
- 别名
- CD100 / SEMA4D (SEMA4D 产品)
- 别名
- C9orf164 antibody, CD100 antibody, M-sema-G antibody, SEMAJ antibody, coll-4 antibody, Semacl2 antibody, Semaj antibody, Semcl2 antibody, COLL-4 antibody, semaphorin 4D antibody, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antibody, Sema4d antibody, SEMA4D antibody
- 背景
- CD100, also known as Sema4D or collapsin-4, is a 150 kDa transmembrane glycoprotein belonging to group IV of the semaphorin family. The CD100 dimer activates T-cells and modifies B-cell signaling through CD40 by promoting B-cell aggregation and survival and by down-regulating CD23 expression. It also regulates B cell responses by down-regulating the inhibitory signal from its receptor, CD72. This signal is turned off when CD100 binds to CD72 and induces tyrosine dephosphorylation of CD72. Soluble CD100, released by activated lymphocytes, significantly enhances B-cell responses induced by CD40. CD100 also binds plexin-1, a receptor that is abundantly expressed in fetal brain and kidney.Synonyms: A8, BB18, GR3, SEMAJ, Semaphorin-4D
- 基因ID
- 10090
- UniProt
- O09126
- 途径
- Regulation of Cell Size
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