ATM 抗体 (C-Term)
Quick Overview for ATM 抗体 (C-Term) (ABIN363380)
抗原
See all ATM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with human and mouse ATM protein
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纯化方法
- Antigen affinity purified
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免疫原
- A fragment of human ATM protein expressed in E.coli. The fragment relates to the C-terminal region (within the last third of the protein sequence)
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC/IF : 1/100 - IP : 1/100 to 1/500 - WB : 1/500 to 1/1 000 - IHC: 1/100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.5 mg/mL
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缓冲液
- PBS, glycerol 50 % , Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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别名
- Serine-Protein Kinase ATM
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背景
- Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Involved in Cell cycle, DNA damage, DNA repair.
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基因ID
- 472
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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