beta 2 Adrenergic Receptor (BAR2) (AA 1-30), (N-Term) 抗体
适用: 人
WB
宿主: 兔
Polyclonal
RB10325
unconjugated
1 image
(2 references)-
- 抗原
- beta 2 Adrenergic Receptor (BAR2)
- 抗原表位
- AA 1-30, N-Term
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB)
- 特异性
- This BAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7~37 amino acids from the N-terminal region of human BAR2.
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This beta 2 Adrenergic Receptor (BAR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human beta 2 Adrenergic Receptor (BAR2).
- 克隆位点
- RB10325
- 亚型
- Ig Fraction
-
- 应用备注
- WB = 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.42 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Enhanced humoral immunity in mice lacking CB1 and CB2 receptors (Cnr1-/-/Cnr2-/- mice) is not due to increased splenic noradrenergic neuronal activity." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 4, pp. 544-57, (2014) (PubMed).
: "Matrix metalloproteinases cleave the beta2-adrenergic receptor in spontaneously hypertensive rats." in: American journal of physiology. Heart and circulatory physiology, Vol. 299, Issue 1, pp. H25-35, (2010) (PubMed).
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: "Enhanced humoral immunity in mice lacking CB1 and CB2 receptors (Cnr1-/-/Cnr2-/- mice) is not due to increased splenic noradrenergic neuronal activity." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 4, pp. 544-57, (2014) (PubMed).
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- 抗原
- beta 2 Adrenergic Receptor (BAR2)
- 背景
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This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Synonyms: Beta-2 adrenoceptor, Beta-2 adrenoreceptor, ADRB2, ADRB2R, B2AR - 分子量
- 46426 DA
- 基因ID
- 154
- NCBI登录号
- NP_000015
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