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RUNX2 抗体 (pSer465)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in DB. Suitable for 人. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN389942
发货至: 中国

Quick Overview for RUNX2 抗体 (pSer465) (ABIN389942)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB15321
  • 抗原表位

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    pSer465

    特异性

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S533 of human RUNX2.

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RUNX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S465 of human RUNX2.

    亚型

    Ig Fraction
  • 应用备注

    DB = 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Fu, Wang, Lu, Ma, Ke, Liu, Luo: "In vitro inhibitory effects of terpenoids from Chloranthus multistachys on epithelial-mesenchymal transition via down-regulation of Runx2 activation in human breast cancer." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 1, pp. 165-72, (2015) (PubMed).

    Wang, Cai, Ma, Liu, Ke, Lu, Fu: "The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cells." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 11, pp. 1017-26, (2015) (PubMed).

    Fu, Ke, Tan, Liu, Wang, Ma, Lu: "The natural compound codonolactone attenuates TGF-?1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells." in: Oncology reports, (2015) (PubMed).

    Wang, Chen, Zou, Tu, Tan, Lu, Liu, Fu: "Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2." in: International journal of oncology, Vol. 45, Issue 5, pp. 1891-900, (2014) (PubMed).

    Tsimbouri, Murawski, Hamilton, Herzyk, Oreffo, Gadegaard, Dalby: "A genomics approach in determining nanotopographical effects on MSC phenotype." in: Biomaterials, Vol. 34, Issue 9, pp. 2177-84, (2013) (PubMed).

    Tsimbouri, McMurray, Burgess, Alakpa, Reynolds, Murawski, Kingham, Oreffo, Gadegaard, Dalby: "Using nanotopography and metabolomics to identify biochemical effectors of multipotency." in: ACS nano, Vol. 6, Issue 11, pp. 10239-49, (2012) (PubMed).

    McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: "Skeletal stem cell physiology on functionally distinct titania nanotopographies." in: Biomaterials, Vol. 32, Issue 30, pp. 7403-10, (2011) (PubMed).

    Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Synonyms: Runt-related transcription factor 2, Core-binding factor subunit alpha-1, CBF-alpha-1, Acute myeloid leukemia 3 protein, Oncogene AML-3, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A

    分子量

    56648 DA

    基因ID

    860

    UniProt

    Q13950
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