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HIST1H3A 抗体 (AA 131-230) (Alexa Fluor 594)

Name: HIST1H3A 抗体 (AA 131-230) (Alexa Fluor 594)
SKU: ABIN2814110
Availability: OutOfStock

HIST1H3A 适用: 人, 小鼠, 大鼠, 绵羊 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594

产品编号 ABIN2814110

发货至: 中国

Datasheet as PDF

抗原 See all HIST1H3A 抗体

HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))
抗原表位
15

8

6

6

6

6

5

5

5

5

5

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
AA 131-230
适用
242

66

49

15

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 绵羊
宿主
235

6

1
兔
Compatible Secondaries
克隆类型
176

66
多克隆
标记
224

3

2

2

1

1

1

1

1

1

1

1

1

1

1
This HIST1H3A antibody is conjugated to Alexa Fluor 594
应用范围
203

182

73

68

62

58

52

27

19

16

16

12

12

8

5
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 大鼠, 绵羊

预测反应

Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human HIF3 alpha

亚型

IgG

Top Product

Discover our top product HIST1H3A Primary Antibody
anti-Histone Cluster 1, H3a (HIST1H3A) (meLys4) antibody
HIST1H3A 适用: 人, 小鼠 ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (3meLys9) antibody
HIST1H3A 适用: 人, 小鼠 ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (3meLys36) antibody
HIST1H3A 适用: 人, 小鼠, Arabidopsis, Oryza sativa ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (acLys14), (acLys9) antibody
HIST1H3A 适用: 人, 小鼠, 斑马鱼, Arabidopsis, Rainbow Trout, Aspergillus nidulans ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (acLys27) antibody
HIST1H3A 适用: 人, 小鼠, 大鼠, Arabidopsis ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (pSer10) antibody
HIST1H3A 适用: 人 ELISA, WB, IF, ChIP, DB 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (3meLys27), (pSer28) antibody
HIST1H3A 适用: 人 ELISA, WB, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (acLys4) antibody
HIST1H3A 适用: 人 ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (acLys18) antibody
HIST1H3A 适用: 人, 小鼠 ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone Cluster 1, H3a (HIST1H3A) (2meArg17 (asymetric)), (acLys18) antibody
HIST1H3A 适用: 人, 小鼠 ELISA, WB, IF, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

应用备注

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))

别名

H3 alpha (HIST1H3A 产品)

别名

H3/A antibody, H3FA antibody, histone cluster 1 H3 family member a antibody, histone cluster 1, H3a antibody, HIST1H3A antibody, Hist1h3a antibody

背景

Synonyms: IPAS, MOP7, PASD7, HIF-3A, bHLHe17, Hypoxia-inducible factor 3-alpha, HIF-3-alpha, HIF3-alpha, Basic-helix-loop-helix-PAS protein MOP7, Class E basic helix-loop-helix protein 17, HIF3-alpha-1, Inhibitory PAS domain protein, Member of PAS protein 7, PAS domain-containing protein 7, HIF3A
Background: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea (By similarity).

基因ID

64344

UniProt

Q9Y2N7