Factor 10 Heavy Chain 抗体 (Alexa Fluor 594)
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- 抗原
- Factor 10 Heavy Chain
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Activated factor Xa heavy chain
- 亚型
- IgG
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anti-Factor 10 Heavy Chain (AA 351-448) antibody
适用: 人, 小鼠 WB, IF (p), IF (cc), IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Factor 10 Heavy Chain
- 别名
- FX antibody, FXA antibody, Cf10 antibody, fX antibody, coagulation factor X antibody, F10 antibody
- 背景
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Synonyms: Activated factor Xa heavy chain, Coagulation factor, Coagulation factor X, EC 3.4.21.6, F10 antibody FA10_HUMAN, Factor Xa, FX, FXA, OTTHUMP00000018735, Prothrombinase, Stuart factor, Stuart Prower factor, Stuart-Prower factor, Coagulation factor X, Factor X heavy chain.
Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor X (Stuart Prower factor, FX, F10) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. The mature form of Factor X (Factor X A) is generated by Factor IX A- or Factor VII A-mediated cleavage at the tripeptide sequence, Arg-Lys-Arg, to yield a disulfide linked dimer. Together with the cofactor Factor V A and Ca2+ on the surface of platelets or endothelial cells, Factor X A coordinates as part of the prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Mutations at the Factor X locus resulting in Factor X deficiencies can contribute to hemorrhagic diathesis.
- 基因ID
- 2159
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