Copa/Alpha Cop I (AA 451-550) 抗体 (Alexa Fluor 594)
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- 抗原
- Copa/Alpha Cop I
- 抗原表位
- AA 451-550
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 594
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human COPA/alpha COP I
- 亚型
- IgG
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-
- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Copa/Alpha Cop I
- 背景
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Synonyms: Alpha coat protein, Alpha COP, Alpha COPI, AlphaCOP, Coatomer protein complex subunit alpha, Coatomer subunit alpha, COP A, COP I alpha, COPA, COPI alpha, FLJ26320, HEP COP, HEPCOP, Proxenin, Xenin, Xenopsin-related peptide, COPA_HUMAN.
Background: COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).
- 基因ID
- 1314
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