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CRTC2 抗体 (pSer171) (Alexa Fluor 594)

CRTC2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2807131
发货至: 中国
  • 抗原 See all CRTC2 抗体
    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
    抗原表位
    • 15
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer171
    适用
    • 66
    • 21
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 58
    • 6
    • 4
    • 1
    克隆类型
    • 62
    • 7
    多克隆
    标记
    • 30
    • 7
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRTC2 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 61
    • 43
    • 19
    • 16
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
    亚型
    IgG
    Top Product
    Discover our top product CRTC2 Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
    别名
    TORC2 (CRTC2 产品)
    别名
    CRTC2 antibody, TORC-2 antibody, TORC2 antibody, 4632407F12Rik antibody, Torc2 antibody, mTORC2 antibody, RGD1308903 antibody, CREB regulated transcription coactivator 2 antibody, CRTC2 antibody, Crtc2 antibody
    背景

    Synonyms: TORC2, TORC-2, CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, Transducer of CREB protein 2, CRTC2

    Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    基因ID
    200186
    UniProt
    Q53ET0
    途径
    AMPK Signaling, Carbohydrate Homeostasis
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