Nfia/Nf-1 (AA 41-140) 抗体 (Alexa Fluor 594)
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- 抗原
- Nfia/Nf-1
- 抗原表位
- AA 41-140
- 适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NFIA/NF-1
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Nfia/Nf-1
- 背景
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Synonyms: CCAAT binding transcription factor, CCAAT Box Binding Transcription Factor, CCAAT-box-binding transcription factor, CTF, FLJ39164, NF I/A, NF-I/A, NF1 A, NF1-A, NF1A, NFI A, NFI L, NFI-A, NFIA, NFIA_HUMAN, Nuclear Factor 1 A, Nuclear factor 1 A type, Nuclear factor 1 A-type, Nuclear factor 1/A, Nuclear Factor 1A, Nuclear Factor I A, Nuclear factor I/A, nuclear factor I/X CCAAT-binding transcription factor, ynuclear factor I/X CCAAT-binding transcription factor, Nuclear factor I/X, Nuclear Factor IA, TGGCA binding protein, TGGCA-binding protein.
Background: NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
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