MEIS3 抗体 (AA 121-220) (Alexa Fluor 594)
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- 抗原 See all MEIS3 抗体
- MEIS3 (Meis Homeobox 3 (MEIS3))
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抗原表位
- AA 121-220
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEIS3 antibody is conjugated to Alexa Fluor 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Mouse,Dog,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Meis homeobox 3
- 亚型
- IgG
- Top Product
- Discover our top product MEIS3 Primary Antibody
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anti-Meis Homeobox 3 (MEIS3) (AA 1-261) antibody
MEIS3 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 1-261) antibodyMEIS3 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 178-264) antibodyMEIS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 1-110) antibodyMEIS3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 252-301) antibodyMEIS3 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 非洲爪蟾, 猴, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 301-350) antibodyMEIS3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 180-229) antibodyMEIS3 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Meis Homeobox 3 (MEIS3) (AA 1-421) antibodyMEIS3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MEIS3 (Meis Homeobox 3 (MEIS3))
- 别名
- Meis homeobox 3 (MEIS3 产品)
- 别名
- XMeis3 antibody, mrg2 antibody, meis1 antibody, MEIS3P1 antibody, MRG2 antibody, meis3 antibody, AI573393 antibody, Mrg2 antibody, NH10 antibody, fc22g05 antibody, id:ibd3530 antibody, meis3.1 antibody, wu:fc22g05 antibody, Meis homeobox 3 S homeolog antibody, Meis homeobox 3 antibody, Meis homeobox 3 L homeolog antibody, myeloid ecotropic viral integration site 3 antibody, meis3.S antibody, meis3 antibody, MEIS3 antibody, meis3.L antibody, Meis3 antibody
- 背景
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Synonyms: Homeobox protein meis3, Meis1 myeloid ecotropic viral integration site 1 homolog 3, Meis1 related protein 2, Meis1-related protein 2 antibodymeis3, MEIS3_HUMAN, MRG2.
Background: Hox, Pbx and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Hox proteins are involved in regulating tissue patterning during development, and are also expressed in lineage- and stage-specific patterns during adult hematopoietic differentiation and in leukemias. The Hox proteins, which include paralog groups 1-10, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx- related Meis proteins, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site. Both Meis1 and Meis2 (also known as Meis-related gene 1 or Mrg1) are members of the TALE (three amino acid loop extension?) family of homeodomain-containing proteins. In addition to binding with Hox proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA-binding specificities. Like Hox and Pbx proteins, Meis1 is implicated in oncogenesis, as it is overexpressed as a result of adjacent retroviral insertion in BHX-2 myeloid leukemias. Two Meis-related proteins, Meis2 and Meis3 (also designated Mrg1 and Mrg2, respectively), possess largely similar sequence identity with Meis1 and are expressed in normal tissues and myeloid leukemias. In the pancreas, Meis2 preferentially associates with Pbx1, and together they associate with the pancreas-specific homeodomain factor, Pdx1, to repress Pdx1-induced transcriptional activation.
- 途径
- Chromatin Binding
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