TLR8 抗体 (C-Term)
Quick Overview for TLR8 抗体 (C-Term) (ABIN2798863)
抗原
See all TLR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 957-987, C-Term
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原理
- Rabbit Anti-Mouse Mouse TLR8 (C-term) Antibody
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免疫原
- This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50TLR8 Antibody (E972) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.460 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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别名
- TLR8
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背景
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Target Description: TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Gene Symbol: Tlr8
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分子量
- 119358 Da
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基因ID
- 170744
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UniProt
- P58682
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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