RPA1 抗体 (C-Term)
Quick Overview for RPA1 抗体 (C-Term) (ABIN2798585)
抗原
See all RPA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 531-559, C-Term
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原理
- Rabbit Anti-Human RPA1 (C-term) Antibody
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免疫原
- This RPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human RPA1.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000RPA1 Antibody (C-term) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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别名
- RPA1
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背景
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Target Description: RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Gene Symbol: RPA1
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分子量
- 68138 Da
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基因ID
- 6117
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UniProt
- P27694
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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