PCDHGB4 抗体 (Center)
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- 抗原 See all PCDHGB4 抗体
- PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
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抗原表位
- AA 353-379, Center
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCDHGB4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit Anti-Human PCDHGB4 (Center) Antibody
- 免疫原
- This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PCDHGB4 Primary Antibody
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- 应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000PCDHGB4 Antibody (Center). - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.300 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
- 别名
- PCDHGB4 (PCDHGB4 产品)
- 别名
- CDH20 antibody, FIB2 antibody, PCDH-GAMMA-B4 antibody, protocadherin gamma subfamily B, 4 antibody, PCDHGB4 antibody, Pcdhgb4 antibody
- 背景
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Target Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.
Gene Symbol: PCDHGB4
- 分子量
- 99927 Da
- 基因ID
- 8641
- UniProt
- Q9UN71
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