IL1A 抗体 (C-Term)
Quick Overview for IL1A 抗体 (C-Term) (ABIN2794894)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 474-503, C-Term
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原理
- Rabbit Anti-Human IL1R (C-term E487) Antibody
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免疫原
- This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of anti-IL1R , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.368 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL1
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背景
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Target Description: IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Gene Symbol: IL1R1
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分子量
- 65402 Da
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基因ID
- 3554
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UniProt
- P14778
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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