KIR2DL2 抗体 (C-Term)
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- 抗原 See all KIR2DL2 抗体
- KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
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抗原表位
- AA 263-291, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIR2DL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Rabbit Anti-Human KIR2DL2 (C-Term) Antibody
- 免疫原
- This KIR2DL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human KIR2DL2.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KIR2DL2 Primary Antibody
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- 应用备注
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Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50KIR2DL2 Antibody (C-Term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.320 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
- 别名
- KIR2DL2 (KIR2DL2 产品)
- 别名
- NKAT6 antibody, p58.2 antibody, CD158b antibody, CD158B1 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 antibody, KIR2DL2 antibody
- 背景
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Target Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Gene Symbol: KIR2DL2
- 分子量
- 38472 Da
- 基因ID
- 3803
- UniProt
- P43627
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