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GTPase NRas 抗体 (C-Term)

This anti-GTPase NRas antibody is a 兔 多克隆 antibody detecting GTPase NRas in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN2793206
发货至: 中国

Quick Overview for GTPase NRas 抗体 (C-Term) (ABIN2793206)

抗原

See all GTPase NRas (NRAS) 抗体
GTPase NRas (NRAS)

适用

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宿主

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克隆类型

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多克隆

标记

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This GTPase NRas antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 147-179, C-Term

    原理

    Rabbit Anti-Human NRAS (C-term) Antibody

    免疫原

    This NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the C-terminal region of human NRAS.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50, FC: 1:10-50NRAS Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    GTPase NRas (NRAS)

    别名

    NRAS

    背景

    Target Description: NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).

    Gene Symbol: NRAS

    分子量

    21229 Da

    基因ID

    4893

    UniProt

    P01111

    途径

    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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