TBP 抗体 (Middle Region)
(1 reference)-
- 抗原 See all TBP 抗体
- TBP (TATA Box Binding Protein (TBP))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 兔, 绵羊, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TBP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FSSGKMVCTG AKSEEQSRLA ARKYARVVQK LGFPAKFLDF KIQNMVGSCD
- 交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TBP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TBP
- Top Product
- Discover our top product TBP Primary Antibody
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anti-TATA Box Binding Protein (TBP) (AA 1-144) antibody
TBP 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7G11C8 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 210-239) antibodyTBP 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) antibodyTBP 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 830CT4-3-3 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 301-330) antibodyTBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) antibodyTBP 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (N-Term) antibodyTBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (AA 39-50) antibodyVerified TBP 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (AA 210-239) antibodyTBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated
anti-TATA Box Binding Protein (TBP) antibodyTBP 适用: 人, 小鼠, 大鼠, Cynomolgus WB, IHC (p), IF (cc) 宿主: 小鼠 Monoclonal 8C4 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 8-316) antibodyTBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB Suggested Anti-TBP Antibody Titration: 2.5 µg/mL
Positive Control: Human Placenta.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 339 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease." in: Brain research. Molecular brain research, Vol. 125, Issue 1-2, pp. 120-8, (2004) (PubMed).
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: "TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease." in: Brain research. Molecular brain research, Vol. 125, Issue 1-2, pp. 120-8, (2004) (PubMed).
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- 抗原
- TBP (TATA Box Binding Protein (TBP))
- 别名
- TBP (TATA-box-binding protein) (TBP 产品)
- 别名
- GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody
- 背景
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Alias Symbols: HDL4, GTF2D, SCA17, TFIID, GTF2D1
Protein Interaction Partner: DR1, SSX2IP, GOLGA2, MEF2A, TAF8, GNG12, GNB2, UBC, UBE2I, TAF10, TAF5, HNF4A, E2F1, PAX5, TAF1A, TCEA1, RUVBL2, Abt1, GTF2A2, ICE2, tat, MED26, TBP, TAF6, TAF4, TAF1, SP1, TP53, SNAPC2, SNAPC1, MUC1, Taf1c, Taf1b, GTF2B, HCVgp1, AHR, TAF9B, BTAF1, TAF13,
Protein Size: 339 - 分子量
- 38 kDa
- 基因ID
- 6908
- NCBI登录号
- NM_003194, NP_003185
- UniProt
- P20226
- 途径
- WNT signaling
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