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TBP 抗体 (Middle Region)

Name: TBP 抗体 (Middle Region)
SKU: ABIN2792684
Availability: OutOfStock

This anti-TBP antibody is a 兔多克隆 antibody detecting TBP in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 犬, 绵羊和豚鼠. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-TBP Antibody Titration: 2. (TBP 抗体 (Middle Region))

1 image

(1 reference)

产品编号 ABIN2792684

发货至: 中国

Quick Overview for TBP 抗体 (Middle Region) (ABIN2792684)

抗原

See all TBP 抗体

TBP (TATA Box Binding Protein (TBP))

适用

人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 犬, 绵羊, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This TBP antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product TBP Primary Antibody

抗原表位
15

10

5

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2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region

序列

FSSGKMVCTG AKSEEQSRLA ARKYARVVQK LGFPAKFLDF KIQNMVGSCD

交叉反应

牛, 犬, 小鸡, 人, 小鼠, 大鼠

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against TBP. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human TBP
anti-TATA Box Binding Protein (TBP) (AA 1-144) antibody
TBP 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7G11C8 unconjugated

anti-TATA Box Binding Protein (TBP) (AA 210-239) antibody
TBP 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) antibody
TBP 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 830CT4-3-3 unconjugated

anti-TATA Box Binding Protein (TBP) (AA 301-330) antibody
TBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (AA 39-50) antibody
Verified TBP 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (N-Term) antibody
TBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (AA 210-239) antibody
TBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated

anti-TATA Box Binding Protein (TBP) antibody
TBP 适用: 人, 小鼠, 大鼠, Cynomolgus WB, IHC (p), IF (cc) 宿主: 小鼠 Monoclonal 8C4 unconjugated

anti-TATA Box Binding Protein (TBP) (AA 8-316) antibody
TBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (AA 1-55) antibody
TBP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB Suggested Anti-TBP Antibody Titration: 2.5 µg/mL
Positive Control: Human Placenta.
Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 339 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Reid, van Roon-Mom, Wood, Rees, Owen, Faull, Dragunow, Snell: "TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease." in: Brain research. Molecular brain research, Vol. 125, Issue 1-2, pp. 120-8, (2004) (PubMed).
抗原

TBP (TATA Box Binding Protein (TBP))

别名

TBP (TATA-box-binding protein)

背景

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Alias Symbols: HDL4, GTF2D, SCA17, TFIID, GTF2D1
Protein Interaction Partner: DR1, SSX2IP, GOLGA2, MEF2A, TAF8, GNG12, GNB2, UBC, UBE2I, TAF10, TAF5, HNF4A, E2F1, PAX5, TAF1A, TCEA1, RUVBL2, Abt1, GTF2A2, ICE2, tat, MED26, TBP, TAF6, TAF4, TAF1, SP1, TP53, SNAPC2, SNAPC1, MUC1, Taf1c, Taf1b, GTF2B, HCVgp1, AHR, TAF9B, BTAF1, TAF13,
Protein Size: 339

分子量

38 kDa

基因ID

6908

NCBI登录号

NM_003194, NP_003185

UniProt

P20226

途径

WNT signaling