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GTF2H2 抗体 (N-Term)

GTF2H2 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792639
发货至: 中国
  • 抗原 See all GTF2H2 抗体
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    抗原表位
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 36
    • 18
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 马, 斑马鱼, 犬
    宿主
    • 32
    • 5
    克隆类型
    • 33
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GTF2H2 antibody is un-conjugated
    应用范围
    • 18
    • 12
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DILFKAKRKR VFEHHGQVRL GMMRHLYVVV DGSRTMEDQD LKPNRLTCTL
    交叉反应
    牛, 犬, 小鸡, 人, 小鼠, 大鼠
    预测反应
    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against GTF2H2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H2
    Top Product
    Discover our top product GTF2H2 Primary Antibody
  • 应用备注
    WB Suggested Anti-GTF2H2 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 395 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    别名
    GTF2H2 / BTF2P44 (GTF2H2 产品)
    别名
    44kDa antibody, BTF2 p44 antibody, BTF2-p44 antibody, Btf2p44 antibody, p44 antibody, BTF2 antibody, BTF2P44 antibody, T-BTF2P44 antibody, TFIIH antibody, general transcription factor II H, polypeptide 2 antibody, general transcription factor IIH subunit 2 antibody, general transcription factor IIH, polypeptide 2, 44kDa antibody, Gtf2h2 antibody, GTF2H2 antibody
    背景
    GTF2H2 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. GTF2H2 is the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-15 BM083743.1 1-15 16-1121 AF078847.1 1-1106 1122-1537 BG283896.1 128-543 1538-1951 AC044797.5 132110-132523 c
    Alias Symbols: BTF2, BTF2P44, MGC102806, T-BTF2P44, TFIIH, p44
    Protein Interaction Partner: UBC, CDK7, GTF2H5, GTF2H1, SRA1, GTF2H4, GTF2H3, UBD, COPS2, ERCC3, ERCC8, ERCC2, AR, MNAT1, CCNH,
    Protein Size: 395
    分子量
    44 kDa
    基因ID
    2966
    NCBI登录号
    NM_001515, NP_001506
    UniProt
    Q13888
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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