MYBL2 抗体 (N-Term)
Quick Overview for MYBL2 抗体 (N-Term) (ABIN2792568)
抗原
See all MYBL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - N-Term
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序列
 - RCEDLDELHY QDTDSDVPEQ RDSKCKVKWT HEEDEQLRAL VRQFGQQDWK
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交叉反应
 - 牛, 犬, 小鸡, 人, 大鼠
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预测反应
 - Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 92%, Rat: 78%, Zebrafish: 83%
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产品特性
 - This is a rabbit polyclonal antibody against MYBL2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
 - Affinity Purified
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免疫原
 - The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2
 
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应用备注
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                        WB Suggested Anti-MYBL2 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 
                                            
说明
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Antigen size: 700 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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                                            : "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2."    in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, (2004)         (PubMed).        
 
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                                            : "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2."    in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, (2004)         (PubMed).        
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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别名
 - MYBL2
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背景
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                        Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Alias Symbols: BMYB, B-MYB
Protein Interaction Partner: CCNA1, CDK2, CCNE1, LIN54, SPTBN1, SPTA1, FLNA, CLTC, CLTA, LIN9, UBE2D4, CXCR4, LIN52, LIN37, RBL1, RBBP4, SUMO2, MAP1LC3B, MAPK6, NLK, HIPK2, CREBBP, ZBTB9, TRIM15, LZTR1, CDK9, ZNF622, UBB, TTF2, EP300, SND1, SKP2, MYBL2, NCOR1, NCOR2, PARP1, CCND1, CC
Protein Size: 700 - 
                                            
分子量
 - 79 kDa
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基因ID
 - 4605
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NCBI登录号
 - NM_002466, NP_002457
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UniProt
 - P10244
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途径
 - Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
 
抗原
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