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MYBL2 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-MYBL2 antibody specifically detects MYBL2 in WB 和 IHC. The antibody is reactive with 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2792568
发货至: 中国
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Quick Overview for MYBL2 抗体 (N-Term) (ABIN2792568)

抗原

See all MYBL2 抗体
MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

适用

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人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This MYBL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    RCEDLDELHY QDTDSDVPEQ RDSKCKVKWT HEEDEQLRAL VRQFGQQDWK

    交叉反应

    牛, 犬, 小鸡, 人, 大鼠

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 92%, Rat: 78%, Zebrafish: 83%

    产品特性

    This is a rabbit polyclonal antibody against MYBL2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2
  • 应用备注

    WB Suggested Anti-MYBL2 Antibody Titration: 0.2-1 µg/mL
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 700 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tashiro, Sumi, Uozumi, Shimizu, Nakamura: "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, (2004) (PubMed).

  • 抗原

    MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

    别名

    MYBL2

    背景

    Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
    Alias Symbols: BMYB, B-MYB
    Protein Interaction Partner: CCNA1, CDK2, CCNE1, LIN54, SPTBN1, SPTA1, FLNA, CLTC, CLTA, LIN9, UBE2D4, CXCR4, LIN52, LIN37, RBL1, RBBP4, SUMO2, MAP1LC3B, MAPK6, NLK, HIPK2, CREBBP, ZBTB9, TRIM15, LZTR1, CDK9, ZNF622, UBB, TTF2, EP300, SND1, SKP2, MYBL2, NCOR1, NCOR2, PARP1, CCND1, CC
    Protein Size: 700

    分子量

    79 kDa

    基因ID

    4605

    NCBI登录号

    NM_002466, NP_002457

    UniProt

    P10244

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
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