CHRNB3 抗体 (Middle Region)
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- 抗原 See all CHRNB3 抗体
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
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抗原表位
- Middle Region
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适用
- 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRNB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YDGTMVDLIL INENVDRKDF FDNGEWEILN AKGMKGNRRD GVYSYPFITY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CHRNB3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB3
- Top Product
- Discover our top product CHRNB3 Primary Antibody
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anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (AA 67-218) antibody
CHRNB3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (AA 25-232) antibodyCHRNB3 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 4C1H2 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (AA 128-223) antibodyCHRNB3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (Internal Region) antibodyCHRNB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (AA 176-225) antibodyCHRNB3 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, Cow, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (AA 187-200) antibodyCHRNB3 适用: Hamster WB 宿主: 兔 Polyclonal RB49738 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (Internal Region) antibodyVerified CHRNB3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 458 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
- 别名
- CHRNB3 (CHRNB3 产品)
- 别名
- 5730417K16Rik antibody, Acrb3 antibody, NACHR antibody, CHRNB3 antibody, chrnb3 antibody, cholinergic receptor nicotinic beta 3 subunit antibody, neuronal acetylcholine receptor subunit beta-3 antibody, cholinergic receptor, nicotinic, beta polypeptide 3 antibody, cholinergic receptor, nicotinic beta 3 L homeolog antibody, cholinergic receptor, nicotinic beta 3 antibody, cholinergic receptor, nicotinic, beta 3b (neuronal) antibody, cholinergic receptor, nicotinic, beta polypeptide 3a antibody, CHRNB3 antibody, CpipJ_CPIJ012638 antibody, Chrnb3 antibody, chrnb3.L antibody, chrnb3 antibody, chrnb3b antibody, chrnb3a antibody
- 背景
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Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction.
Protein Size: 458 - 分子量
- 53 kDa
- 基因ID
- 1142
- NCBI登录号
- NM_000749, NP_000740
- UniProt
- Q05901
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