-
- 抗原 See all DOK1 抗体
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
-
抗原表位
- C-Term
-
适用
- 人, 马
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DOK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- EPGTATGSGI KSHNSALYSQ VQKSGASGSW DCGLSRVGTD KTGVKSEGST
- 预测反应
- Horse: 84%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DOK1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DOK1
- Top Product
- Discover our top product DOK1 Primary Antibody
-
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-280) antibody
DOK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) antibodyDOK1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (Internal Region) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) antibodyDOK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) antibodyDOK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr362) antibodyDOK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) antibodyDOK1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr362) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibodyDOK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 481 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- 别名
- DOK1 (DOK1 产品)
- 别名
- P62DOK antibody, Dok-1 antibody, AW557123 antibody, p62DOK antibody, dok1 antibody, zgc:76914 antibody, docking protein 1 antibody, docking protein 1b antibody, DOK1 antibody, Dok1 antibody, dok1b antibody
- 背景
-
DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
Alias Symbols: MGC117395, MGC138860, P62DOK
Protein Interaction Partner: UBC, RASA1, ABL1, CD28, Nck1, Syngap1, INSR, CRKL, BCR, Dlg4, gag-pol, ERBB2, VAV1, SRC, SHC1, PTK6, PIK3R1, ITK, FGR, CRK, ABL2, CBLL1, INPP5D, NCK2, MAP4K4, PTPRH, GRB10, TEC, ITGB2, SH2D1A, FES, PTPN6, ITGB3, PLCG1, LYN, KIT, YES1, RET, LCK, ITGB5, ITG
Protein Size: 481 - 分子量
- 53 kDa
- 基因ID
- 1796
- NCBI登录号
- NM_001381, NP_001372
- UniProt
- Q99704
-
You are here:
