RIPK1 抗体 (Middle Region)
Quick Overview for RIPK1 抗体 (Middle Region) (ABIN2792131)
抗原
See all RIPK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RRRRVSHDPF AQQRPYENFQ NTEGKGTAYS SAASHGNAVH QPSGLTSQPQ
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预测反应
- Cow: 100%, Dog: 91%, Horse: 83%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against RIPK1. It was validated on Western Blot using a cell lysate as a positive control.
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RIPK1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 671 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
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别名
- RIPK1
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背景
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FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.
Alias Symbols: RIP, RIP1
Protein Interaction Partner: RFFL, RIPK1, UBC, TRAF2, TRAF1, TNFRSF1A, TNF, OTUD1, YOD1, TRADD, IKBKG, FADD, CASP8, MAP3K7, BMH1, BIRC3, BIRC2, MAP3K8, OPTN, NUMBL, CFLAR, HSP90AA1, RIPK3, USP4, TNFAIP3, TNFSF10, LRRK2, TNFRSF10B, MAP3K3, HHV8GK18_gp80, DAB2IP, TNFRSF1B, IKBKB, CHUK,
Protein Size: 671 -
分子量
- 76 kDa
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基因ID
- 8737
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NCBI登录号
- NM_003804, NP_003795
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UniProt
- Q13546
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
抗原
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