-
- 抗原 See all BIRC7 抗体
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
-
抗原表位
- Middle Region
-
适用
- 人, Cow, 犬, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This BIRC7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- EERTCKVCLD RAVSIVFVPC GHLVCAECAP GLQLCPICRA PVRSRVRTFL
- 预测反应
- Cow: 85%, Dog: 84%, Human: 100%, Rabbit: 92%
- 产品特性
- This is a rabbit polyclonal antibody against BIRC7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BIRC7
- Top Product
- Discover our top product BIRC7 Primary Antibody
-
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 101-200) antibody
BIRC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibodyBIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyVerified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 298 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
- 别名
- BIRC7 (BIRC7 产品)
- 别名
- KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
- 背景
-
BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Alias Symbols: KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Protein Interaction Partner: FAM124B, DIABLO, POLR1C, UBE2D2, PHF1, DDX6, CASP9, BIRC2, AES, CASP3, RAF1, XIAP, TAB1, HTRA2, UBC, BIRC7, UBE2I, UBE2E1, UBE2D3, UBE2D1, UBE2K, CASP7, XAF1,
Protein Size: 298 - 分子量
- 33 kDa
- 基因ID
- 79444
- NCBI登录号
- NM_139317, NP_647478
- UniProt
- Q96CA5
-
You are here:
