BIRC7 抗体
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- 抗原 See all BIRC7 抗体
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BIRC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Fluorescence Microscopy (FM)
- 纯化方法
- Anti-Livin Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Livin from human based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Livin from other sources has not been determined.
- 免疫原
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Immunogen: Livin Antibody was produced in mice prepared by repeated immunizations with recombinant human protein, Livin.
Immunogen Type: Recombinant Protein
- 克隆位点
- 88C570
- 亚型
- IgG1
- Top Product
- Discover our top product BIRC7 Primary Antibody
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- 应用备注
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Application Note: Anti-Livin antibody is suitbable for use in IF/ICC and WB. Expect a band approximately 30 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1-2 μg/mL
IF Microscopy Dilution: 2-5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
- 别名
- Livin (BIRC7 产品)
- 别名
- KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
- 背景
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Synonyms: KIAP, LIVIN, MLIAP, RNF50, BIRC7, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50
Background: Anti-Livin BIRC7 KIAP antibody detects human Livin BIRC7 KIAP. The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain, has been identified. Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain. Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells. Livin expression is low in adult tissues. It is relatively expressed at a higher level in developmental tissues and in many cancer cells. Anti-Livin BIRC7 KIAP antibody is ideal for investigators invovled in apoptosis reasearch.
Gene Name: BIRC7
- 基因ID
- 79444
- NCBI登录号
- NP_071444
- UniProt
- Q96CA5
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