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BIRC7 抗体 (N-Term)

Name: BIRC7 抗体 (N-Term)
SKU: ABIN6263273
Availability: OutOfStock

BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of ML-IAP using K562 whole cell lysates (BIRC7 抗体 (N-Term))

1 image

产品编号 ABIN6263273

发货至: 中国

Datasheet as PDF

抗原 See all BIRC7 抗体

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
抗原表位
15

8

7

6

5

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
58

15

15

2

2

2

1
人
宿主
50

6

2
兔
Compatible Secondaries
克隆类型
51

6
多克隆
标记
34

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This BIRC7 antibody is un-conjugated
应用范围
51

20

15

14

13

13

10

6

5

4

3

3

1

1

1

1

1

1
Western Blotting (WB), ELISA

特异性

ML-IAP Antibody detects endogenous levels of total ML-IAP.

预测反应

Pig,Rabbit

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ML-IAP, corresponding to a region within N-terminal amino acids.

亚型

IgG

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BIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibody
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anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibody
Verified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibody
BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibody
BIRC7 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1B10 unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibody
BIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

别名

BIRC7 (BIRC7 产品)

别名

KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody

背景

Description: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
Gene: BIRC7

分子量

32 kDa

基因ID

79444

UniProt

Q96CA5