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- 抗原 See all TRADD 抗体
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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抗原表位
- Middle Region
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适用
- 人, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRADD antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YEQAFQLLRR FVQAEGRRAT LQRLVEALEE NELTSLAEDL LGLTDPNGGL
- 预测反应
- Dog: 76%, Horse: 76%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TRADD. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRADD
- Top Product
- Discover our top product TRADD Primary Antibody
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anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibodyTRADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A1E8 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibodyTRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18788 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibodyTRADD 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 312 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- 别名
- TRADD (TRADD 产品)
- 背景
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TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hs.89862, MGC11078
Protein Interaction Partner: FADD, UBC, TNF, RIPK1, TNFRSF1A, ZMYND11, TOMM70A, PDLIM7, LRRK2, OPTN, TRADD, TRAF2, TRAF1, TNFRSF1B, GFRA1, CHUK, FAS, DAB2IP, EDAR, CDKN2A, TRIP12, LMP1, CASP8, SH3KBP1, USP2, TNFRSF25, PPP2R1A, TRPC4AP, HIPK2, TNFRSF21, CNTRL, TNFRSF10B, TNFRSF10A, BC
Protein Size: 312 - 分子量
- 34 kDa
- 基因ID
- 8717
- NCBI登录号
- NM_003789, NP_003780
- UniProt
- Q15628
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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