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TRADD 抗体 (Middle Region)

Name: TRADD 抗体 (Middle Region)
SKU: ABIN2792121
Availability: OutOfStock

This 兔多克隆 anti-TRADD antibody specifically detects TRADD in WB. The antibody is reactive with 人, 犬和马 samples.

WB Suggested Anti-TRADD Antibody Titration: 0. (TRADD 抗体 (Middle Region))

Lanes: Lane 1: 10ug Tradd-HA-Strep-stable expression 293TREXFlpIn cells-Doxycycline induced Lane 2: 10ug ITradd-HA-Strep-stable expression 293TREXFlpIn cells-non-induced Lane 3: 10ug siRNA scrambled-MDA-MB-231 cells Lane 4: siRNA Tradd-MDA-MB-231 cells Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: TRADD Submitted by: Dr. (TRADD 抗体 (Middle Region))

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产品编号 ABIN2792121

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TRADD 抗体 (Middle Region) (ABIN2792121)

抗原

See all TRADD 抗体

TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

适用

人, 犬, 马

宿主

兔

克隆类型

多克隆

标记

This TRADD antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product TRADD Primary Antibody

抗原表位
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Middle Region

序列

YEQAFQLLRR FVQAEGRRAT LQRLVEALEE NELTSLAEDL LGLTDPNGGL

预测反应

Dog: 76%, Horse: 76%, Human: 100%

产品特性

This is a rabbit polyclonal antibody against TRADD. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human TRADD
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibody
TRADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibody
TRADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibody
TRADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A1E8 unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibody
TRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibody
TRADD 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18788 unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibody
TRADD 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibody
TRADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibody
TRADD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibody
TRADD 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2230 unconjugated Recombinant Antibody

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 312 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

别名

TRADD

背景

TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hs.89862, MGC11078
Protein Interaction Partner: FADD, UBC, TNF, RIPK1, TNFRSF1A, ZMYND11, TOMM70A, PDLIM7, LRRK2, OPTN, TRADD, TRAF2, TRAF1, TNFRSF1B, GFRA1, CHUK, FAS, DAB2IP, EDAR, CDKN2A, TRIP12, LMP1, CASP8, SH3KBP1, USP2, TNFRSF25, PPP2R1A, TRPC4AP, HIPK2, TNFRSF21, CNTRL, TNFRSF10B, TNFRSF10A, BC
Protein Size: 312

分子量

34 kDa

基因ID

8717

NCBI登录号

NM_003789, NP_003780

UniProt

Q15628

途径

NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C