TRADD 抗体 (Middle Region)
Quick Overview for TRADD 抗体 (Middle Region) (ABIN2792121)
抗原
See all TRADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YEQAFQLLRR FVQAEGRRAT LQRLVEALEE NELTSLAEDL LGLTDPNGGL
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预测反应
- Dog: 76%, Horse: 76%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against TRADD. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRADD
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anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibodyTRADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A1E8 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibodyTRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18788 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibodyTRADD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 203-312) antibodyTRADD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G3 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 312 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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别名
- TRADD
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背景
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TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hs.89862, MGC11078
Protein Interaction Partner: FADD, UBC, TNF, RIPK1, TNFRSF1A, ZMYND11, TOMM70A, PDLIM7, LRRK2, OPTN, TRADD, TRAF2, TRAF1, TNFRSF1B, GFRA1, CHUK, FAS, DAB2IP, EDAR, CDKN2A, TRIP12, LMP1, CASP8, SH3KBP1, USP2, TNFRSF25, PPP2R1A, TRPC4AP, HIPK2, TNFRSF21, CNTRL, TNFRSF10B, TNFRSF10A, BC
Protein Size: 312 -
分子量
- 34 kDa
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基因ID
- 8717
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NCBI登录号
- NM_003789, NP_003780
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UniProt
- Q15628
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
抗原
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