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IGF1R 抗体 (Middle Region)

Name: IGF1R 抗体 (Middle Region)
SKU: ABIN2792087
Availability: OutOfStock

IGF1R 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, Pig, 马, 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-IGF1R Antibody Titration: 0. (IGF1R 抗体 (Middle Region))

Image no. 1 for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody (ABIN2792087) (IGF1R 抗体 (Middle Region))

Immunofluorescent IGF1R detection in mouse skeletal muscle (red fluorescence). (IGF1R 抗体 (Middle Region))

IHC

3 images

(1 reference)

产品编号 ABIN2792087

发货至: 中国

Datasheet as PDF

抗原 See all IGF1R 抗体

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
抗原表位
26

24

24

14

13

11

10

10

7

6

6

5

5

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region
适用
188

116

97

15

6

6

6

3

3

1

1

1

1

1

1
人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, Pig, 马, 绵羊
宿主
175

27

2

1
兔
Compatible Secondaries
克隆类型
177

28
多克隆
标记
119

9

8

7

7

7

7

7

7

7

4

3

3

3

3

3

2
This IGF1R antibody is un-conjugated
应用范围
126

68

58

54

32

25

17

13

13

10

5

4

4

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

序列

DRHSGHKAEN GPGPGVLVLR ASFDERQPYA HMNGGRKNER ALPLPQSSTC

特异性

Directed to the beta chain of IGF1R

预测反应

Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against IGF1R. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human IGF1R

Top Product

Discover our top product IGF1R Primary Antibody
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1346) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibody
IGF1R 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01458 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibody
IGF1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1101-1367) antibody
IGF1R 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3G5C1 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr980) antibody
IGF1R 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1367 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kubota, Elalieh, Saless, Fong, Wang, Babey, Cheng, Bikle: "Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading." in: Acta astronautica, Vol. 92, Issue 1, pp. 73-78, (2013) (PubMed).
抗原

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

别名

IGF1R (IGF1R 产品)

别名

CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody

背景

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-140 DR007209.1 566-705 141-3559 X04434.1 136-3554 3560-4540 BC113610.1 3542-4522 4541-4921 DA486252.1 187-567 4922-5392 BX093045.1 248-718 5393-5768 CN414655.1 317-692 5769-6158 BM264223.1 185-574 6159-6580 BQ185364.1 187-608 6581-11242 AC069029.9 21278-25939 c
Alias Symbols: CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216, IGFR
Protein Interaction Partner: KCNIP3, UBC, ESR1, PHB2, SHC1, FBXO6, SH2B1, Slc23a3, RPL11, HSP90AA1, GRB14, FFAR2, ARRB2, AMY2A, APP, RUVBL1, GNB2L1, ARRB1, YWHAG, TP53, NEDD4, MDM2, GRB10, SUMO1, CAMP, ERBB2, EGFR, KRT27, DOK5, DOK4, WISP2, EHD1, ARHGEF12, PIK3R3, VAV3, PRKD1, SOCS2,
Protein Size: 1367

分子量

71 kDa

基因ID

3480

NCBI登录号

NM_000875, NP_000866

UniProt

P08069

途径

RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy