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IGF1R 抗体 (Middle Region)

This 兔多克隆 antibody specifically detects IGF1R in WB, IHC 和 IF. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, Pig, 马和绵羊.It has been mentioned in 1 publication

Image no. 1 for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody (ABIN2792087) (IGF1R 抗体 (Middle Region))

Immunofluorescent IGF1R detection in mouse skeletal muscle (red fluorescence). (IGF1R 抗体 (Middle Region))

IHC

3 images

(1 reference)

产品编号 ABIN2792087

发货至: 中国

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Quick Overview for IGF1R 抗体 (Middle Region) (ABIN2792087)

抗原

See all IGF1R 抗体

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, Pig, 马, 绵羊

宿主

兔

克隆类型

多克隆

标记

This IGF1R antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product IGF1R Primary Antibody

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Middle Region

序列

DRHSGHKAEN GPGPGVLVLR ASFDERQPYA HMNGGRKNER ALPLPQSSTC

特异性

Directed to the beta chain of IGF1R

预测反应

Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against IGF1R. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human IGF1R
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1346) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibody
IGF1R 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibody
IGF1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01458 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibody
IGF1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr980) antibody
IGF1R 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 763-955) antibody
IGF1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1367 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kubota, Elalieh, Saless, Fong, Wang, Babey, Cheng, Bikle: "Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading." in: Acta astronautica, Vol. 92, Issue 1, pp. 73-78, (2013) (PubMed).
抗原

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

别名

IGF1R

背景

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-140 DR007209.1 566-705 141-3559 X04434.1 136-3554 3560-4540 BC113610.1 3542-4522 4541-4921 DA486252.1 187-567 4922-5392 BX093045.1 248-718 5393-5768 CN414655.1 317-692 5769-6158 BM264223.1 185-574 6159-6580 BQ185364.1 187-608 6581-11242 AC069029.9 21278-25939 c
Alias Symbols: CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216, IGFR
Protein Interaction Partner: KCNIP3, UBC, ESR1, PHB2, SHC1, FBXO6, SH2B1, Slc23a3, RPL11, HSP90AA1, GRB14, FFAR2, ARRB2, AMY2A, APP, RUVBL1, GNB2L1, ARRB1, YWHAG, TP53, NEDD4, MDM2, GRB10, SUMO1, CAMP, ERBB2, EGFR, KRT27, DOK5, DOK4, WISP2, EHD1, ARHGEF12, PIK3R3, VAV3, PRKD1, SOCS2,
Protein Size: 1367

分子量

71 kDa

基因ID

3480

NCBI登录号

NM_000875, NP_000866

UniProt

P08069

途径

RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy