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- 抗原 See all SPTA1 抗体
- SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 马, 兔, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPTA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DELSGWMNEK TAAINADELP TDVAGGEVLL DRHQQHKHEI DSYDDRFQSA
- 预测反应
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPTA1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPTA1
- Top Product
- Discover our top product SPTA1 Primary Antibody
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anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 940-1160) antibody
SPTA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTA1-1832 unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rSPTA1-1832 unconjugated Recombinant Antibody
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal SPTA1-2939R unconjugated Recombinant Antibody
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTA1-1810 unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
- 别名
- SPTA1 (SPTA1 产品)
- 别名
- Spna1 antibody, AF093576 antibody, AI451697 antibody, Spna-1 antibody, ha antibody, ihj antibody, nmf4 antibody, sph antibody, EL2 antibody, HPP antibody, HS3 antibody, SPH3 antibody, SPTA antibody, spectrin, alpha, erythrocytic 1 antibody, spectrin alpha, erythrocytic 1 antibody, Spta1 antibody, SPTA1 antibody
- 背景
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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Alias Symbols: EL2, HPP, HS3, SPH3, SPTA
Protein Interaction Partner: ANK1, PTPRO, UBC, YWHAQ, MYBL2, PTPN22, BTK, UBASH3B, SHC1, CBL, FASLG, NCOA3, ENAH, EVL, SPTBN2, ABI1, VASP, PLEC, SLC9A2, FANCC, SPTB, ADD1, ACTA1, ABL1, EZR, FANCA, ERCC4,
Protein Size: 2419 - 分子量
- 266 kDa
- 基因ID
- 6708
- NCBI登录号
- NM_003126, NP_003117
- UniProt
- P02549
- 途径
- Regulation of Actin Filament Polymerization
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