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SPTA1 抗体 (N-Term)

This anti-SPTA1 antibody is a 兔 多克隆 antibody detecting SPTA1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2792075
发货至: 中国

Quick Overview for SPTA1 抗体 (N-Term) (ABIN2792075)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔

宿主

  • 19
  • 9

克隆类型

  • 15
  • 13
多克隆

标记

  • 21
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPTA1 antibody is un-conjugated

应用范围

  • 18
  • 11
  • 9
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 8
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    DELSGWMNEK TAAINADELP TDVAGGEVLL DRHQQHKHEI DSYDDRFQSA

    预测反应

    Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SPTA1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPTA1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    SPTA1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
    Alias Symbols: EL2, HPP, HS3, SPH3, SPTA
    Protein Interaction Partner: ANK1, PTPRO, UBC, YWHAQ, MYBL2, PTPN22, BTK, UBASH3B, SHC1, CBL, FASLG, NCOA3, ENAH, EVL, SPTBN2, ABI1, VASP, PLEC, SLC9A2, FANCC, SPTB, ADD1, ACTA1, ABL1, EZR, FANCA, ERCC4,
    Protein Size: 2419

    分子量

    266 kDa

    基因ID

    6708

    NCBI登录号

    NM_003126, NP_003117

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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