ERK1 抗体 (N-Term)
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北京 101111
Quick Overview for ERK1 抗体 (N-Term) (ABIN2792053)
抗原
See all ERK1 (MAPK3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GGGGGEPRRT EGVGPGVPGE VEMVKGQPFD VGPRYTQLQY IGEGAYGMVS
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预测反应
- Human: 100%, Pig: 79%
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产品特性
- This is a rabbit polyclonal antibody against MAPK3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MAPK3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
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别名
- MAPK3
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背景
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Protein Interaction Partner: MAPK1, DUSP4, STAR, RAF1, PTGDR, MAP2K1, NAB2, MYOG, DHPS, HDAC6, MAGED1, AMOT, FOXP2, CDC23, VPS52, L3MBTL3, TRIM54, DCP1A, UBC, TP53, PTGS2, RPS6KA2, MAPK3, PHF3, TEK, MBP, ELK1, CUEDC2, MAPKAPK2, GAB2, IRX2, ADAM15, VCP, ELK4, DAPK1, Rara, IQGAP1, TP53
Protein Size: 357 -
分子量
- 39 kDa
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基因ID
- 5595
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途径
- MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins
抗原
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