CD51 抗体 (C-Term)
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- 抗原 See all CD51 (ITGAV) 抗体
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 马, 兔, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD51 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PVWVIILAVL AGLLLLAVLV FVMYRMGFFK RVRPPQEEQE REQLQPHENG
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ITGAV. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV
- Top Product
- Discover our top product ITGAV Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1002 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- 别名
- ITGAV (ITGAV 产品)
- 别名
- 1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
- 背景
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ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: CD51, DKFZp686A08142, MSK8, VNRA
Protein Interaction Partner: UBC, EPHA2, THBS1, FN1, KRT3, MCAT, FBXO6, BCAR1, PXN, PHKA2, CSF1R, CBL, MMP2, ILK, PLP1, CALR, ANGPTL3, EDIL3, CYR61, PAK4, ITGB8, ADAM9, AUP1, CD47, PTK2, MMP14, P2RY2, L1CAM, AZGP1, TGFB1, THY1, F2R, PDGFRA, ITGB3, SPP1, ITGB5, ITGB6, ITGB1, NID1, ICA
Protein Size: 1002 - 分子量
- 100 kDa
- 基因ID
- 3685
- NCBI登录号
- NM_001144999, NP_001138471
- UniProt
- E7EWZ6
- 途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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