FCGR3A 抗体 (Middle Region)
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- 抗原 See all FCGR3A 抗体
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FCGR3A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DPIHLRCHSW KNTALHKVTY LQNGKGRKYF HHNSDFYIPK ATLKDSGSYF
- 预测反应
- Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against FCGR3A. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product FCGR3A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 253 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- 别名
- FCGR3A (FCGR3A 产品)
- 别名
- CD16 antibody, CD16A antibody, FCG3 antibody, FCGR3 antibody, FCGRIII antibody, FCR-10 antibody, FCRIII antibody, FCRIIIA antibody, IGFR3 antibody, Fcgr4 antibody, Fc fragment of IgG receptor IIIa antibody, FCGR3A antibody, Fcgr3a antibody
- 背景
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This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Protein Interaction Partner: SYK, ZBTB25, APP, IGHG1, GP6, SHC1, CD4, CD247, ZAP70, LCK, PTPRC, FCER1G, FCGR1A, CD38, APCS,
Protein Size: 253 - 分子量
- 27 kDa
- 基因ID
- 2214
- NCBI登录号
- NM_001127596, NP_001121068
- UniProt
- P08637
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