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- 抗原 See all IL4 Receptor (IL4R) 抗体
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL4 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GLDREPPRSP QSSHLPSSSP EHLGLEPGEK VEDMPKPPLP QEQATDPLVD
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against IL4R. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL4R
- Top Product
- Discover our top product IL4R Primary Antibody
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anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibody
IL4R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-233) antibodyIL4R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 201-300) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4B12B12 unconjugated
anti-Interleukin 4 Receptor (IL4R) (N-Term) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 1-227) antibodyIL4R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (Ser540) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 别名
- IL4R (IL4R 产品)
- 别名
- IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
- 背景
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This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Protein Interaction Partner: UBC, JAK3, CD40, STAT6, JAK2, JAK1, IL2RG, SOCS5, KAT5, HGS, ARIH2, INPP5D, DOK2, IRS2, SHC1, IL13RA1, NCF1, FES, PRKCZ, GNB2L1, PTPN6, PTPN11, IL4, IL13, IRS1,
Protein Size: 825 - 分子量
- 87 kDa
- 基因ID
- 3566
- UniProt
- P24394
- 途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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