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- 抗原 See all MRGPRX1 抗体
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRGPRX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FLSALNSSAN PIIYFFVGSF RQRQNRQNLK LVLQRALQDA SEVDEGGGQL
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MRGPRX1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRGPRX1
- Top Product
- Discover our top product MRGPRX1 Primary Antibody
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anti-MAS-Related GPR, Member X1 (MRGPRX1) antibody
MRGPRX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (N-Term) antibodyMRGPRX1 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) antibodyMRGPRX1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (C-Term) antibodyMRGPRX1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (Extracellular Domain) antibodyMRGPRX1 适用: 人, 猴 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (AA 263-322) antibodyMRGPRX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (AA 271-320) antibodyMRGPRX1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 322 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
- 别名
- MRGPRX1 (MRGPRX1 产品)
- 别名
- GPCR antibody, MRGX1 antibody, SNSR4 antibody, MrgC11 antibody, Mrgprc11 antibody, Snsr1 antibody, MAS related GPR family member X1 antibody, MAS-related GPR, member X1 antibody, MRGPRX1 antibody, Mrgprx1 antibody
- 背景
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MRGPRX1 is an orphan receptor. MRGPRX1 is probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRX1 is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. MRGPRX1 is activated by the antimalarial drug, chloroquine and may mediate chloroquine-induced itch, in an histamine-independent manner.
Alias Symbols: GPCR, MRGX1, SNSR4
Protein Interaction Partner: GNG2, GNB1, GNAQ, GNAI2,
Protein Size: 322 - 分子量
- 36 kDa
- 基因ID
- 259249
- NCBI登录号
- NM_147199, NP_671732
- UniProt
- Q96LB2
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